Serratiopeptidase (Serratia E-15 protease, also known as serralysin, serratiapeptase, serrapeptase serratia peptidase, serratio peptidase, or serrapeptidase) is a proteolytic enzyme (protease) produced in the laboratory by enterobacterium Serratia sp. E-15 from plant material. This microorganism was originally isolated in the late 1960:s from silkworm Bombyx mori L. (intestine), Serratiopeptidase is present in the silkworm intestine and allows the emerging moth to dissolve its cocoon. Serratiopeptase is produced by purification from culture of Serratia E-15 bacteria.

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